January 27, 2021

synthesis of salicylic acid lab report

The general theory behind this experiment was to study the synthesis of a drug from organic materials. As the reaction proceeds, the solid salicylic acid disappears and the acetylsalicylic acid product remains dissolved in the hot solution. BACKGROUND. You will mix iron (III) nitrate with salicylic acid in your aspirin sample to complex the salicylic acid, which is a bluish-purple color. SYNTHESIS OF SALICYLIC ACID The purpose of this experiment is to synthesize salicylic acid, a white organic solid that was extracted from willow bark by Hippocrates in the fifth century BC. 3 g of calciumnitrate tetrahydrate is dissolved in 10 ml of acetic acid within a 100 ml conical flask by gently heating on a water bath. 3. PROCEDURE. Salicylic acid synthesis lab report >>> next page Essay about my favorite game badminton About sample essays read an academic essay analyse an academic all of the reference items start with the title of the information source. Synthesis of Salicylic Acid from Wintergreen Oil. Turned off burner when mixture was clear. Beaker. Reactions: Procedure and Results: Aspirin Synthesis Tap water was heated on a steam bath in a 250 mL beaker. The phenol group that will attack the carbonyl carbon of the acetic anhydride is the –OH group that is directly attached to the benzene since it is more basic than the –OH group attached to the carbonyl group. Synthesis of Salicylic Acid Lab Report Introduction The purpose of the experiment is to convert oil of coralberry into salicylic window pane by a base-catalyzed hydrolysis reaction. Preparation of Aspirin Lab Report. Aspirin is an organic ester. Organic Chemistry. The temperature of an alcohol thermometer was equilibrated in a beaker of room temperature tap water. Organic synthesis provided a 61% yield of the acid, a relatively low yield. So, concentration of salicylic acid in my ASA product is ± 1.5%. Flashcards. You will analyze several samples to determine the amount of salicylic acid impurity in your synthesized aspirin. Synthesis of Aspirin Aspirin is the single most manufactured drug in the world. Synthesis of salicylic acid from alkyl salicylate . Illustration of the combinatorial synthesis of azo dyes with chemical names 2-aminobenzene- sulfonic acid 3-aminobenzene- sulfonic acid 4-aminobenzene- sulfonic acid 4-nitroaniline 1-naphthol 2-naphthol salicylic acid 8-anilino- 1-naphthalene- sulfonic acid, ammonium salt At that time salicylic acid was known to ease pains and reduce fevers. Summary: In this lab, we synthesized Aspirin using both acid catalysis and base catalysis. Gravity. 11 SYNTHESIS OF ASPIRIN (Acetylsalicylic acid from salicylic acid) Jennie Marie. 02 2008. Hippocrates’ discovery was lost over time, but re-discovered in the mid 1700’s. Possible essay questions what does shakespeare suggest about the role of women in hamlet? The darker the colour, the more salicylic acid is present in the solution. As a catalyst, H+ is regenerated (not consumed) by the end of the reaction. Funnel. Spell. LAB REPORT FOR EXPERIMENT 3 COPPER CYCLE OLANREWAJU OYINDAMOLA TUESDAY 27TH February 2013 Abstract This experiment is based on copper, to synthesize some copper compound using Copper (II) nitrate solution to obtain copper metal at the end. PLAY. Online Marketing and Product Launch Consultant. 11 February 2014 During the experiment, esterification had occurred between reactants salicylic acid and acetic anhydride. Lab Report: Synthesis of Aspirin xperimental Duta Mass of flask 73.801 74.80 215 Mass of flask and salicylic acid Mass of watch glass Mass of watch glass and crude aspirin product 3. REQUIREMENTS. CHE143 - Lab Report : Organic Synthesis - Formation of An Ester (2015) Nurlina Syahiirah. Get Your Custom Essay on Synthesis of Aspirin Lab Report Created by. About; VIP Day; Workshops; Services; Blog; Contact; SEARCH EME BASSEY. Test. Lab awareness must be constantly maintained. Use: Used in organic drug synthesis.. This acid will then be used to make aspirin. Learn more. These molecular entities were created by covalently linking two bioactive molecules, either niacin or salicylic acid, to an omega-3 fatty acid. Key Concepts: Terms in this set (60) How can new pharmaceuticals be discovered? The purpose of this lab was to learn how to use salicylic acid to make aspirin. Salicylic superman is a white, crystalline compound. This product will be impure because of unreacted salicylic acid and visible spectroscopy can help determine the percentage of the impurity of the product. Introduction: The purpose of this experiment was to make aspirin via esterification, and to determine the percent yield we as a lab group made. Abstract: The objective of this experiment was to synthesize aspirin from salicylic acid and acetic anhydride. The by-product is acetic acid (Figure 5.1). Aspirin’s chemical name is acetylsalicylic acid, and it is synthesized from the reaction of acetic anhydride with salicylic acid in the presence of phos-phoric acid as a catalyst. Aspirin Synthesis and Analysis Revised: 12/13/14 reaction complex. Synthesis Of Aspirin Lab Report. Chemicals: Salicylic acid – 2 g. Acetic acid – 10 ml. Home Synthesis of salicylic acid from alkyl salicylate. The experiment aimed at synthesizing salicylic acid from methyl salicylate and determining the acid dissociation constant Ka of the acid along with its purity. Calculate the amount of moles of methyl salicylate and record on line (2) in the Table 1. moles = g / Molar Mass Calculate the theoretical yield of salicylic acid and record on line (3) in Table 1. Usually, esters are derived from a carboxylic acid and alcohol. The full balanced molecular equation for the salicylic acid synthesis is C 8 H 8 O 3 + 2 NaOH + H 2 SO 4 -> C 4 H 6 O 3 + Na 2 SO 4 + CH 3 OH + H 2 O. Lab A - Synthesis of Salicylic Acid. Calciumnitrate tetrahydrate – 3 g. Apparatus: Conical flask. Since the limiting reagent is the reactant that is completely consumed in the reaction we need to calculate moles. Your synthesis converted most, but not all, of the salicylic acid into acetylsalicylic acid. This is a lab report on the “Synthesis of Organic Aspirin” As shown in Figure 1 we see that the equation is balanced on both the reactant and product side. Write. how does shakespeare present the idea of madness in hamlet. 2008. 993 Words 4 Pages. Synthesis of Aspirin (Acetylsalicylic Acid) Using Acid and Base Catalysis CHM 2211C: Organic Chemistry II January 30, 2013 Synthesis of Aspirin (Acetylsalicylic Acid) Using Acid and Base Catalysis. STUDY. Esters are derived from an acid (organic or inorganic) in which at least one -OH (hydroxyl) group is replaced by an alkyl group. -Isolating a natural product and identifying its medicinal properties-Chemically synthesizing a new drug. karla gonzales chem 3220.303 synthesis of aspirin summary: in this experiment, we are synthesizing aspirin reacting salicylic acid with acetic anhydride and Record the weight of methyl salicylate used on line (1) of Table 1. E. Orbiso Group Number II CHEM 40.1 – 7L I. It is usually used for the removal of warts from the skin. An illustrated equation showing compounds to be isolated or synthesized is shown below. Changes … Do not get distracted. Table 2. "Synthesis Of Salicylic Acid From Wintergreen Oil Lab Report" Essays and Research Papers . During the first day of this lab, we will produce salicylic acid. The synthesis of aspirin is a multi-billion dollar a year chemical. ellezee96. Rasan Cherala Synthesis of Aspirin lab Purpose: The purpose of this experiment is to create aspirin by reacting salicylic acid with acetic anhydride. Let mixture settle and then vacuum filtered the mixture. 1 0 obj Acid, % Yield= (Actual yield)/(Theoretical Yield) * 100% ⇒⇒⇒WRITE-MY-PAPER.net ⇐⇐⇐ I love this site. Match. Don't use plagiarized sources. Once all solid has disappeared (all the salicylic acid has Filter paper. 121 - 130 of 500 . While salicylic acid as some therapuetic value, it is not as effective as aspirin in reducing inflammation and other common medical conditions for which aspirin can be used. ABSTRACTIn chemical engineering or in chemical subject, there is a chemical compound named esters. Aspirin is an analgesic anti-inflammatory drug. RELATED WORK: Synthesis of Aspirin Lab Report . Exercise No. Introduction Synthesizing an organic compound is an important knowledge or tool in the organic industry. In my product, I observed visible violet colour that corresponded to the amount of salicylic acid between 1% and 2% according to the reference solutions provided in the lab. Principle: Alkaline hydrolysis of esters is called saponification and is an irreversible process. After synthesis and analysis, it will be deter-mined if the crude and recrystallized samples were composed solely of either salicylic acid, acetylsalicylic acid, or a combination of both (3). Synthesis of Aspirin By: Jon Torre Purpose: To determine which of four catalysts yields the fastest reaction rate in the acetylation of salicylic acid (1) to form acetylsalicylic acid (2). Small changes in a molecule. Learn. Show More. Salicylic acid was esterfied using acetic acid and sulfuric acid acting as a catalyst to produce acetylsalicylic acid and acetic acid. Melting Point of the recrystallized salicylic acid: 125-130ᵒC. An ester is a compound that is formed when an acid reacts with an alcohol, -OH group. The salicylic acid turned into a dark purple color when mixed with the iron (Ill) chloride solution, which was expected since salicylic acid has phenol groups. This report describes the synthesis and preliminary biological characterization of novel fatty acid niacin conjugates and fatty acid salicylate conjugates. Synthesized is shown below alcohol, -OH group of unreacted synthesis of salicylic acid lab report acid was known to pains... This product will be impure because of unreacted salicylic acid into acetylsalicylic acid from Wintergreen Oil Lab Report Table.! Lab, we will produce salicylic acid and acetic anhydride acid ) Jennie.! Shakespeare present the idea of madness in hamlet the solid salicylic acid impurity in your synthesized aspirin this Report the... 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